In rare cases, more adverse side effects like kidney or liver dysfunction can occur
Oral Ozempic Delivers Mixed Results on Alcohol Use Semaglutide in pill form shows promise for alcohol use disorder STUDY: Schacht JP et al, American Journal of Psychiatry 2026 STUDY TYPE: Randomized, double-blind, placebo-controlled trial FUNDING: National Institute on Alcohol Abuse and Alcoholism, National Center for Advancing Translational Sciences, Hewit Family Foundation, anonymous donor Background GLP-1 drugs like semaglutide (Ozempic) have a mix of positive and negative data in alcohol use disorder, but most of the research has involved non-treatment seeking populations, which often differ in their responses
Side effects: Common Side Effects: 1
Calorie restriction appears to affect neurobiological pathways that control appetite, hunger, cravings and body weight, such that there is increased food intake and weight gain (Brown et al, 2022)