RSV may exhibit biphasic redox behavior, acting as an antioxidant under oxidative stress conditions but inducing pro-oxidant effects in physiological environments or at specific concentrations (de la Lastra and Villegas 2007
Various flavonoids, such as myricetin, kaempferol, quercetin, and inositols (e.g., phytic acid) have been found to inhibit XO in vitro and/or in model animals (Pacher et al., 2006)
MPTP treatment also significantly induced levels of NLRP3 and its downstream signaling components ASC, Caspase 1, cleaved IL-1, indicating inflammasome induction, in the substantia nigra (Fig
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