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SAR444656 and LT-002-158 (oral), and EVO101 (topical) are IRAK4 inhibitors currently being studied in phase I/II clinical trials for HS
Symptoms I Pay Attention To Unusual fatigue Rapid heart rate New digestive issues Anxiety or restlessness Drastic changes in hunger Red Flags Patients Often Ignore Feeling extremely cold Consistent brain fog Dramatic hair shedding No weight loss after 12+ weeks These can signal dose adjustments for thyroid medication, not a problem with GLP-1
Similarly, symptoms of gallbladder disease (such as right upper abdominal pain, fever, or jaundice) require prompt medical assessment, as GLP-1 medications may increase the risk of gallstone formation
Children 6 to 17 years old may require closer monitoring and a subsequent dosage change if during the first few months of taking Zoloft they experience significant weight loss and/or suicidal ideation
