Afterwards, subsequent discoveries have identified increased lactylation in histone and non-histone proteins, particularly with the development of YnLac, an alkynyl-functionalized chemical reporter
Detel D, Buljevic S, Pucar LB, Kucic N, Pugel EP, Varljen J (2016) Influence of CD26/dipeptidyl peptidase IV deficiency on immunophenotypic changes during colitis development and resolution
Moreover, central administration of GIP upregulates hypothalamic mRNA expression of genes regulating food intake and metabolism, including arginine vasopressin ( Avp ), cocaine and amphetamine regulated transcripts ( Cart ), cAMP responsive element binding protein 1 ( Creb1 ), gamma-aminobutyric acid A receptor, subunit delta ( Gabrd ), janus kinase 2 ( Jak2 ), mitogen-activated protein kinase 1 ( Mapk1 ), neuropeptide Y ( Npy ), oxytocin ( Oxt ), signal transducer and activator of transcription 3 ( Stat3 ) and tyrosine hydroxylase ( Th ), which is not observed in whole-body GIPR KO mice 35
Nakamura, H